Conferences, assignments, and laboratory. Elective course. Contract approved by instructor, advisor, and department head is required for undergraduate students.

This four credit hour course instructs students on the important fundamentals that define pharmaceutical sciences. Important concepts of pharmacology, medicinal chemistry and pharmaceutics are taught with the broad goal of understanding pharmaceutical agents at a molecular level. It is the introductory graduate level course for graduate students in the pharmaceutical sciences. It is also intended for graduate students in other related fields of biological, chemical, and biomedical sciences who wish to learn the principles of pharmaceutical sciences.

Addresses recent concepts and technology in the pharmaceutical and biomedical sciences. Assists students in interpreting and evaluating published literature; and, understanding and presenting, in oral or written formats, scientific research in the pharmaceutical and biomedical sciences.

The interaction of natural and synthetic drugs with biological systems at the molecular and quasi-molecular level.

An advanced study of natural and synthetic drugs by pharmacological classes, with emphasis on the application of principles covered in PHAR 703.

A continuation of PHAR 704.

A study of the medicinal analyses of an advanced nature with special emphasis on instrumental methods of medicinal analysis.

A study of the fundamentals of heterocyclic nomenclature and the chemistry of both the heterocyclic medicinal products and the intermediates for their synthesis.

The chemistry and biogenesis of alkaloids and antibiotics.

Lectures, seminars, demonstrations and laboratory work on recent and more technical advances in the field of biochemistry.

Lectures, seminars, demonstrations and laboratory work on recent and more technical advances in the field of biochemistry.

Discussion and presentation of current topics in pharmacy administration. Required of all master’s degree (2 credit hours) and Ph.D. degree (3 credit hours) candidates in the Department of Pharmacy Practice.

Discussion and presentation of current topics in pharmaceutical and health outcomes research. Required of all master’s degree (2 credit hours) and Ph.D. degree (4 credit hours) candidates in the Department of Clinical Pharmacy and Outcomes Sciences.

Discussion and presentation of current topics in Pharmaceutical Outcomes Sciences. Required of all master’s degree (2 credit hours) and Ph.D. degree (4 credit hours) candidates in the Department of Clinical Pharmacy and Outcomes Sciences.

Discussion and presentation of current topics in pharmaceutical and health outcomes research. Required of all master’s degree (2 credit hours) and Ph.D. degree (4 credit hours) candidates in the Department of Clinical Pharmacy and Outcomes Sciences.

Discussion and presentation of current topics in pharmaceutical and health outcomes research. Required of all master’s degree (2 credit hours) and Ph.D. degree (4 credit hours) candidates in the Department of Clinical Pharmacy and Outcomes Sciences.

Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of 4 credit hours may be earned in PHAR 712 A-D.

Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of 4 credit hours may be earned in PHAR 712 A-D.

Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of 4 credit hours may be earned in PHAR 712 A-D.

Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of 4 credit hours may be earned in PHAR 712 A-D.

Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of 4 credit hours may be earned in PHAR 712 A-D.

Application of synthetic procedures in the preparation of various medicinal and pharmaceutical chemicals and their intermediates.

Application of molecular modeling, computer graphics, and other computational techniques to the design of drugs.

Pharmacogenomics concepts and experimental approaches combined with pharmacotherapy realms.

Lectures, readings, and discussions on special areas of experimental pharmacy not offered in other courses.

Lectures, readings, and discussions on special areas of experimental pharmacy not offered in other courses.

A study of the mathematical models used in research to describe drug changes in body fluids as related to pharmacologic effects. Includes the kinetics of dissolution, absorption, distribution, metabolism, and excretion after a drug reaches the general circulation. Three lecture and three laboratory hours per week.

Physical, chemical, and kinetic concepts which apply to the design and evaluation of pharmaceutical systems.

Application of chemical and physical concepts to the design and evaluation of pharmaceutical systems (dosage forms).

The biological effects of ionizing radiation and the basic mechanisms which bring about these effects. Monitoring, dosimetry, hazard control, and legal responsibilities concerning ionizing radiation used in medicine.

Neurochemical analysis of selected central nervous system neurotransmitter topics, including the kinetics of synthesis, storage and release, and the action of selected psychotherapeutic agents on these processes.

The molecular and biochemical basis of cancer and the therapeutic approaches in the prevention and treatment of cancer.

Survey of drugs acting on the autonomic nervous system and the cardiovascular system; advanced topics in these areas and on antibiotics and chemotherapy.

Survey of centrally acting drugs, anti-inflammatory and immunomodulating drugs, hormones, and vitamins; advanced topics in these areas and in drug design and drug toxicity/teratogenesis.

Factors that govern drug response, biochemical and molecular actions of drugs, and adverse effects induced by drugs.

An analysis of practice environments of pharmacists. Emphasis on the drug using public and health care providers in terms of economics, social, and health factors. Detailed analysis of the third-party prescription market including prescribing behavior, drug use, cost containment, legal issues, and quality of care.

Development and use of pharmaceutical outcomes databases.

The nature of the research process in the administrative and behavioral aspects of pharmacy practice. Emphasis on developing the skills to analyze the total drug use process.

Basic components of a competitive grant proposal will be presented and a proposal prepared using the NIH R01 format.

The principles of marketing as applied to pharmaceutical products. Topics include various marketing institutions and the integration of these into the drug distribution system, and the duties of the market manager in a pharmaceutical firm.

The principles of marketing applied to the international pharmaceutical industry. Emphasis on the marketing environment and institutions of pharmaceutical marketing in global markets.

Detailed analysis of the third party prescription market including prescribing behavior, drug use, cost containment, legal issues, and quality of care.

Analytical techniques and theoretical principles for evaluating costs and consequences of pharmaceutical agents and services for the health care system and society.

Theories and methods to identify determinants, develop implementation strategies, and evaluate outcomes of evidence-based health-related programs, interventions, and policies to ensure effective, safe, equitable, and quality care.

Didactic lectures and discussions involving content from relevant textbooks and research literature on the principles of pharmacoepidemiology, research design, and an introduction to statistical techniques used in pharmacoepidemiology.

Directed laboratory research and literature assignments supervised by graduate faculty.