Chemistry, B.S.C


Entrance Requirements

New freshmen who meet University admissions standards are eligible for admission to degree programs offered by the college. A student who wishes to enter the College of Arts and Sciences from another college on the Columbia campus must be in good standing and have a cumulative GPA of 2.00 or higher. A student who wishes to enter the College of Arts and Sciences from another USC campus must fulfill one of the following requirements:

  1. Be in good standing, meet the admission requirements for a baccalaureate degree on the Columbia campus, and have a cumulative GPA of 2.00 or higher.
  2. Be in good standing and have completed 30 semester hours with a GPA of 2.00 or higher on a USC campus.

Some programs in the College of Arts and Sciences have special admission requirements established by the department or committee that supervises the specific degree program, for example, Cardiovascular Technology, Biological Sciences, Chemistry, Biochemistry and Molecular Biology, Economics, Environmental Science, the Bachelor of Arts in Interdisciplinary Studies, and the Bachelor of Science in Interdisciplinary Studies. These requirements are listed in the sections of this bulletin that describe department and special degree programs.

Degree Requirements (120 hours)

Program of Study

Requirements Credit Hours
1. Carolina Core 34-46
2. College Requirements 15-19
3. Program Requirements 26-34
4. Major Requirements 37-38

Founding Documents Requirement

All undergraduate students must take a 3-credit course or its equivalent with a passing grade in the subject areas of History, Political Science, or African American Studies that covers the founding documents including the United State Constitution, the Declaration of Independence, the Emancipation Proclamation and one or more documents that are foundational to the African American Freedom struggle, and a minimum of five essays from the Federalist papers.  This course may count as a requirement in any part of the program of study including the Carolina Core, the major, minor or cognate, or as a general elective.  Courses that meet this requirement are listed here.

1. Carolina Core Requirements (34-46 hours)

CMW – Effective, Engaged, and Persuasive Communication: Written (6 hours)

must be passed with a grade of C or higher

ARP – Analytical Reasoning and Problem Solving (8 hours) 

SCI – Scientific Literacy (8 hours)

must be passed with a grade of C or higher

GFL – Global Citizenship and Multicultural Understanding: Foreign Language (0-6 hours)

Demonstration of proficiency in one foreign language equivalent to the minimal passing grade on the exit examination in the 122 course is required. Students can demonstrate this proficiency by successfully completing Phase II of the Proficiency Test or by successfully completing the 122 course, including the exit exam administered as part of that course.

It is strongly recommended that students continuing the study of a foreign language begin college-level study of that language in their first semester and continue in that language until their particular foreign language requirement is completed.

GHS – ​Global Citizenship and Multicultural Understanding: Historical Thinking (3 hours) 

any CC-GHS course

GSS – Global Citizenship and Multicultural Understanding: Social Sciences (3 hours) 

any CC-GSS course

AIU – Aesthetic and Interpretive Understanding (3 hours)

any CC-AIU course

CMS – Effective, Engaged, and Persuasive Communication: Spoken Component1 (0-3 hours)

any overlay or stand-alone CC-CMS course

INF – Information Literacy1 (0-3 hours)

any overlay or stand-alone CC-INF course

VSR – Values, Ethics, and Social Responsibility1 (0-3 hours)

any overlay or stand-alone CC-VSR course


Carolina Core Stand Alone or Overlay Eligible Requirements — Overlay-approved courses offer students the option of meeting two Carolina Core components in a single course. A maximum of two overlays is allowed. The total Carolina Core credit hours must add up to a minimum of 31 hours. Some programs may have a higher number of minimum Carolina Core hours due to specified requirements.

2. College Requirements (12-19 hours)

Foreign Language (0-3 hours) 

  • only if needed to meet 122-level proficiency

Analytical Reasoning (3-7 hours)

Course Title Credits
CSCE 145Algorithmic Design I (*)4
or CSCE 106 Scientific Applications Programming
STAT 509Statistics for Engineers (*)3
or STAT 515 Statistical Methods I
Total Credit Hours7

Note: If CHEM 111, CHEM 112, CHEM 322, and CHEM 322L (or CHEM 141, CHEM 142, CHEM 322 and CHEM 322L) are all completed at UofSC, STAT 509 or STAT 515 is not required. Also, if CHEM 621 and CHEM 621L are completed, STAT 509 or STAT 515 is not required. Students who exempt STAT 509 or STAT 515 through this process will be required to take an approved elective to reach minimum hours for graduation.

History (3 hours) 

The College of Arts and Sciences requires one additional GHS course beyond the Carolina Core GHS requirement. 

  • If the Carolina Core GHS requirement is fulfilled by a U.S. history course, the College of Arts and Sciences history requirement must be fulfilled by a non-U.S. history course.
  • If the Carolina Core GHS requirement is fulfilled by a non-U.S. history course, the College of Arts and Sciences history requirement must be fulfilled by a U.S. history course. 

Please select the College of Arts and Sciences history requirement from the approved list of U.S. and non-U.S. history courses.

Social Science and Fine Arts or Humanities (6 hours)

  • Social Science (3 hours)
  • Fine Arts/Humanities (3 Hours)

3. Program Requirements (26-37 hours)

Supporting Courses (14 hours)

Course Title Credits
MATH 241Vector Calculus (*)3
One MATH course beyond MATH 241*3
CHEM 141Principles of Chemistry I (*)4
CHEM 142Principles of Chemistry II (*)4
Total Credit Hours14

Note: Students transferring in to the major can substitute CHEM 111/CHEM 111L (or transfer equivalent) for CHEM 141 and CHEM 112/CHEM 112L (or transfer equivalent) for CHEM 142

Cognate (12 hours)

The cognate must consist of twelve (12) hours of courses at the advanced level, outside of but related to the major. The cognate may be taken in one or more departments or programs.

Courses offered by departments and programs that are acceptable for cognate credit are outlined in the section titled Courses Acceptable for Cognate Credit in Degree Programs in the College of Arts and Sciences. Some major programs have specific cognate requirements. It should be emphasized that the cognate is not a second set of elective courses to be chosen at random by the student. Students are urged to consult their major advisors for specific requirements in their major.

For Bachelor of Science degrees, grades of D are acceptable for completion of the cognate requirement, except where restricted by the major program.

Minor (18 hours) optional

In place of the cognate a student in the College of Arts and Sciences may choose a minor consisting of at least 18 credit hours of prescribed courses.

The minor is intended to develop a coherent basic preparation in a second area of study. It differs from the cognate inasmuch as the courses must follow a structured sequence.

Courses applied toward general education requirements cannot be counted toward the minor. No course may satisfy both major and minor requirements. All minor courses must be passed with a grade of C or higher. At least half of the courses in the minor must be completed in residence at the University.

A list of minor programs of study can be found at Programs A-Z.

Electives (0-11 hours)

120 (or 128) degree applicable credits are required to complete any degree at USC. After the cognate, minor or second major is complete, any additional credits needed to reach 120 (or 128) total credits can be fulfilled by electives. No courses of a remedial, developmental, skill-acquiring, or vocational nature may apply as credit toward degrees in the College of Arts and Sciences. The College of Arts and Sciences allows the use of the Pass-Fail option on elective courses. Further clarification on inapplicable courses can be obtained from the College of Arts and Sciences.

4. Major Requirements (37-38 hours)

a minimum grade of C is required in all major courses

Major Courses (37-38 hours)

Course Title Credits
CHEM 322Analytical Chemistry3
CHEM 322LAnalytical Chemistry Laboratory1
CHEM 333Organic Chemistry I3
CHEM 333LComprehensive Organic Chemistry Laboratory I2
CHEM 334Organic Chemistry II3
CHEM 334LComprehensive Organic Chemistry Laboratory II2
CHEM 511Inorganic Chemistry3
CHEM 541Physical Chemistry3
CHEM 541LPhysical Chemistry Laboratory2
CHEM 542Physical Chemistry3
CHEM 542LPhysical Chemistry Laboratory2
CHEM 550Biochemistry3
or CHEM 555 Biochemistry/Molecular Biology I
CHEM 621Instrumental Analysis3
CHEM 621LInstrumental Analysis Lab1
3 credit of undergrdauate research (in an approved area of biochemistry or inorganic chemistry)3
Total Credit Hours37

If the undergraduate research is not in an approved area of biochemistry or inorganic chemistry, CHEM 550L must be taken.

Note: Students who transfer into the program after completion of CHEM 331L and CHEM 332L, may meet the organic chemistry requirements by completing CHEM 334L.

Major Map

A major map is a layout of required courses in a given program of study, including critical courses and suggested course sequences to ensure a clear path to graduation.

Major maps are only a suggested or recommended sequence of courses required in a program of study. Please contact your academic advisor for assistance in the application of specific coursework to a program of study and course selection and planning for upcoming semesters.

Chemistry, B.S.C.